RESUMO
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Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Dermatopatias Papuloescamosas/diagnóstico , Granulomatose com Poliangiite/diagnóstico , Hemoptise/etiologia , Granulomatose com Poliangiite/complicaçõesRESUMO
Kaposi's sarcoma is a multifocal neoplastic process with four clinical variants, all of them induced by human herpes virus 8. Currently there is no treatment of choice and it depends on the extension and location of the lesions as well as on the clinical type of the disease. Alitretinoin gel 0.1 % is approved for the treatment of cutaneous lesions of AIDS-associated Kaposi's sarcoma. The majority of its side effects appear at the site of application and can lead to therapy withdrawal. We report a case of Kaposi's sarcoma treated with topical alitretinoin that had a favourable evolution in spite of an intense local reaction.
Assuntos
Antineoplásicos/administração & dosagem , Sarcoma de Kaposi/tratamento farmacológico , Neoplasias Cutâneas/tratamento farmacológico , Tretinoína/administração & dosagem , Administração Tópica , Idoso de 80 Anos ou mais , Alitretinoína , Feminino , HumanosRESUMO
El sarcoma de Kaposi es un proceso neoplásico multifocal del cual existen 4 variantes clínicas, todas ellas inducidas por el virus herpes humano tipo 8. En la actualidad no existe un tratamiento de elección y éste depende de la extensión y la localización de las lesiones, así como del tipo clínico de la enfermedad. La alitretinoína al 0,1 % en gel está aprobada para el tratamiento de las lesiones cutáneas del sarcoma de Kaposi asociado a sida. La mayoría de sus efectos secundarios aparecen en el lugar de aplicación y pueden obligar a suspender el tratamiento. Presentamos un caso de sarcoma de Kaposi tratado con alitretinoína tópica con buena evolución pese a la intensa reacción local
Kaposi's sarcoma is a multifocal neoplastic process with four clinical variants, all of them induced by human herpes virus 8. Currently there is no treatment of choice and it depends on the extension and location of the lesions as well as on the clinical type of the disease. Alitretinoin gel 0.1 % is approved for the treatment of cutaneous lesions of AIDS-associated Kaposi's sarcoma. The majority of its side effects appear at the site of application and can lead to therapy withdrawal. We report a case of Kaposi's sarcoma treated with topical alitretinoin that had a favourable evolution in spite of an intense local reaction
